I just did some minor disassembly, and oh boy is this the hardest "plug and play" installation I've ever seen.
1. I believe the dynamic brake slot is meant to access the decoder.
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2. The flange makes the board inaccessible from the top. We'll need to find another way in.
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3. The couplers secure the shell onto the body. These need to be removed. The shell then lifts off, but only barely.
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4. You can get a little more room if you remove the fore and aft plugs. But the plugs still have wires running shell to chassis, so this only gets you a few millimeters more room.
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This should give you just enough room to pull the jumper board and replace it with a board of your choice. I'll check if the Loksound fits, but my hopes are not too high. I'll probably just use a NCE board here until ESU comes up with something smaller.
So not an easy installation by any means. It's not impossible, but it feels more like this was an afterthought than planned. You're putting a lot of stress on a lot of small wires. I think this could have been avoided by using ribbon cable with flat anchors on the adapter board instead of the current wire harness. This would save a lot of room and can be folded to allow complete shell removal to access the cable anchor.
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This is a good example of a low profile ribbon connector. This would be a lot more user friendly for access in future BLI engines.