@PiperguyUMD I'm no expert in PE... just dabbling in it myself.
If etching your own, anything that will prints could work.
But the "as a service" guys tend to have specific software they will work with. What I've found is most want a vector file (ex: corel draw or AI). Or they charge you to convert and clean up - which can get excessive fast. I've tried sketch up converted to AI, but I had many issue with shapes not "touching" a so it leaves voids that failed to be converted to a 2D vector file. Got crazy messing so I started fresh... using Rhino (on demo). The unroll feature of Rhino could be super for PE... but after some debate, PEI (
http://www.photofabrication.com/) decided they couldn't take a Rhino file and wanted it converted (corel draw or AI).
Then there is the issue of color coding. While not all shops use the same color coding - and some want a unique flat file for each layer.
Bottom line, from their perspective, it would seem the ideal is to created de novo in a vector file format. And where possible, you may wish to use the service provider's template so you can optimize your design, and thus your output for their equipment, as well as to be formatted for their standard color code.
Good luck and keep us posted!